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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
0.5 DPC

4 matching records from 4 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sox2  SRY (sex determining region Y)-box 2   (Synonyms: lcc, Sox-2, ysb)
Results  Reference
1*J:81180 Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R, Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 2003 Jan 1;17(1):126-40
1*J:175285 Pan H, Schultz RM, Sox2 modulates reprogramming of gene expression in two-cell mouse embryos. Biol Reprod. 2011 Aug;85(2):409-16
1*J:205532 Wang S, Xia P, Ye B, Huang G, Liu J, Fan Z, Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency. Cell Stem Cell. 2013 Nov 7;13(5):617-25
1J:228855 Wicklow E, Blij S, Frum T, Hirate Y, Lang RA, Sasaki H, Ralston A, HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. PLoS Genet. 2014 Oct;10(10):e1004618

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory